Allantoin

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Allantoin
Chemical name
(2,5-Dioxo-4-imidazolidinyl) urea
General
Chemical formula C4H6N4O3
Molecular weight 158.1164 g/mol
Appearance white crystalline powder
CAS number 97-59-6
MSDS Allantoin MSDS
SMILES O=C1C(NC(=O)N1)NC(=O)N
Other names
  • ?
Physical properties
Density and phase at STP  ? g/cm3 (?)
Solubility 0.5% in water (25 °C)
0.2% in alcohol (25 °C ?)
Specific gravity  ?
Crystal structure  ?
pH (10% solution with water)  ?
Acidity constant (pKa)  ?
Thermal decomposition  ? °C (? K)
Phase behavior
Melting point 239 °C
Boiling point  ? °C (? K)
Triple point  ? K (? °C)
 ? bar
Critical point  ? K (? °C)
 ? bar
Heat of fusion
fusH)
 ? kJ/mol
Entropy of fusion
fusS)
 ? J/mol·K
Heat of vaporization
vapH)
 ? kJ/mol

Allantoin is a botanical extract of the comfrey plant and is used for its healing, soothing, and anti-irritating properties[citation needed]. Allantoin helps to heal wounds and skin irritations and stimulate growth of healthy tissue[citation needed]. This extract can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin.

Its chemical formula is C4H6N4O3. It is also called 5-ureidohydantoin or glyoxyldiureide. It is a product of oxidation of uric acid. It is a diureide of glyoxylic acid. It is a product of purine metabolism in most mammals except higher apes, and it is present in their urine.[1]

The keratolytic effect and abrasive and astringent properties of allantoin are used in skin softening cosmetic preparations. It is also frequently present in toothpaste, mouthwash, and other oral hygiene products, in shampoos, lipsticks, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products.

  • udder cream
  • ureidohydantoin
  • glyoxyldiureide
  • hemocane
  • (2,5-dioxo-4-imidazolidinyl)-urea
  • 5-ureidohydantoin
  • (formerly) Vitamin U

  1. ^ Young E. G., Wentworth H. P., Hawkins W. W. (1944). "The absorption and excretion of allantoin in mammals". J. Pharmacol. Experi. Therapeutics 81: 1-9. 
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