Allodynia

From Wikipedia, the free encyclopedia

Allodynia, meaning "other pain", is an exaggerated response to otherwise non-noxious stimuli and can be either static or mechanical. Allodynia is not referred pain and can occur in other areas that are not stimulated; it is also dysesthetic.

For example, a person with allodynia may perceive light pressure or the movement of clothes over the skin as painful, whereas a healthy individual will not feel pain.

One explanation of the mechanism for allodynia is that the associated nerve damage results in decreased firing thresholds of nociceptive fibres.

Alternatively, it has been postulated that peripheral nerve injury could induce collateral sprouting of non-nociceptive primary afferent neurones, such as A-beta low threshold mechanoreceptors, into the superficial (nociceptive) laminae in the dorsal horn of the spinal cord. These collateral branches could form functional contacts with nociceptive second order neurones, normally innervated by C-fibre nociceptive primary afferent neurones and transmit an innocous input as noxious.

Allodynia is a clinical feature of pain conditions such as migraine, postherpetic neuralgia, and neuropathies.

There are different kinds or types of allodynia:

  • Mechanical allodynia (also known as tactile allodynia) - Pain from light touch/pressure applied to the skin in the area of the damaged nerve. Mechanical allodynia can be dynamic or static.
  • Thermal (heat or cold) allodynia - Pain from normally mild skin temperatures in the affected area.
Advanced Search
Included Web Search Engines


Safe Search

close

Top Matching Results

Occasionally Search.com will highlight specialized results that are based on the context of your query. Examples of specialized results include specific links to news, images, or video.

Top Matching Results may highlight information from other Search.com pages, content from the CNET Network of sites, or third party content. The listings are based purely on relevance. Search.com does not receive payment for listings in this section but our partners that provide this data may get paid for listing these products.

Sponsored Links

This section contains paid listings which have been purchased by companies that want to have their sites appear for specific search terms and related content. These listings are administered, sorted and maintained by a third party and are not endorsed by Search.com.

Search Results

Search.com sends your search query to several search engines at one time and integrates the results into one list which has been sorted by relevance using Search.com's proprietary algorithm. You can customize the list of search engines included in your metasearch from the preferences.

The search engines that are used in your metasearch may allow companies to pay to have their Web sites included within the results. To view the Paid Inclusion policy for a specific search engine, please visit their Web site. Search.com does not accept payment or share revenue with any search engine partner for listings in this section.