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Allosteric enzyme
From Wikipedia, the free encyclopedia
The word allosteric comes from the Greek allos,'other' and 'stereos','shape'. This denotes the fact that allosteric enzymes change shape, or conformation, on binding of the modulator. Allosteric enzymes tend to have several subunits.
Allosteric enzymes are regulatory enzymes. In some cases the regulatory site(s) and the active site are on separate subunits.
Allosteric enzymes is an oligomer whose biological activity is affected by other substances binding to it. These substances change the enzyme's activity by altering the conformation(s) of its tertiary structure.
Allosteric effector is a substances that modifies the behavior of an allosteric enzymes; it may be an allosteric inhibitor or allosteric activater.
- Biochemistry 6th Ed, Stryer Berg and Tymoczko