Alpha subunit of glycoprotein hormones
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Alpha subunit of glycoprotein hormones
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| Identifiers | |
| Symbol | CGA |
| HUGO | 1885 |
| Entrez | 1081 |
| OMIM | 118850 |
| RefSeq | NM_000735 |
| UniProt | P01215 |
| Other data | |
| Locus | Chr. 6 q14-q21 |
The Alpha subunit of glycoprotein hormones is a peptide formed by gene found on chromosome 6. It serves as the alpha protein subunit for the following four hormones:
- Human chorionic gonadotropin
- Follicle-stimulating hormone
- Luteinizing hormone
- Thyroid stimulating hormone
Peptide hormones, Steroid hormones
Hypothalamus: TRH, CRH , GnRH, GHRH, somatostatin, dopamine - Posterior pituitary: vasopressin, oxytocin, lipotropin - Anterior pituitary: α (FSH, LH, TSH), GH, prolactin, POMC (ACTH, MSH, endorphins, lipotropin) - Pineal gland: melatonin
Thyroid: thyroid hormone (T3 and T4) - calcitonin - Parathyroid: PTH - Adrenal medulla: epinephrine, norepinephrine - Adrenal cortex: aldosterone, cortisol, DHEA - Pancreas: glucagon- insulin, somatostatin
Kidney: renin, EPO, calcitriol, prostaglandin - Heart atrium: ANP - Stomach: gastrin, ghrelin - Duodenum: CCK, GIP, secretin, motilin, VIP - Ileum: enteroglucagon - Liver: IGF-1 - Adipose tissue: leptin, adiponectin
Testis: testosterone, AMH, inhibin - Ovary: estradiol, progesterone, inhibin/activin, relaxin (pregnancy) - Placenta: hCG, HPL, estrogen, progesterone