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Basal body
From Wikipedia, the free encyclopedia
A basal body is an organelle formed from a centriole, a short cylindrical array of microtubules. It is found at the base of a eukaryotic cell cilium or flagellum and serves as a nucleation site for the growth of the axoneme microtubules. Basal bodies anchor cilia.
Basal bodies are structurally identical to centrioles (they are centrioles).
Regulation of basal body production and spatial orientation is a function of the nucleotide-binding domain of γ-tubulin (Shang et al, 2005).
Y. Shang, C.-C. Tsao, and M. A. Gorovsky. 2005. Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis. J. Cell Biol. 171(6):1035-44. PMID 16344310
- Histology at BU 21804loa - "Ultrastructure of the Cell: ciliated epithelium, cilia and basal bodies"
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