Bendroflumethiazide

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Bendroflumethiazide
Systematic (IUPAC) name
3-benzyl-5,5-dioxo-9- (trifluoromethyl)-5λ6- thia-2,4-diazabicyclo[4.4.0]deca-7, 9,11-triene-8-sulfonamide
Identifiers
CAS number 73-48-3
ATC code C03AA01
PubChem 2315
DrugBank APRD00666
Chemical data
Formula C15H14F3N3O4S2 
Mol. mass 421.417 g/mol
Pharmacokinetic data
Bioavailability 100%
Protein binding 96%
Metabolism extensive
Half life 3-4 hours[1]
Excretion  ?
Therapeutic considerations
Pregnancy cat.

Risk neonatal thrombocytopenia in 3rd trimester[2]
Legal status

POM(UK)
Routes oral

Bendroflumethiazide INN (formerly BAN bendrofluazide), is a thiazide diuretic, used to treat hypertension.

  1. ^ in Ed. Sean C. Sweetman: Martindale: The complete drug reference, 33, Pharmaceutical Press. 
  2. ^ BNF 45 March 2003

v • d • e
Antihypertensives (C02) and diuretics (C03)
Antiadrenergic agents (including alpha) Clonidine, Doxazosin, Guanethidine, Guanfacine, Lofexidine,Mecamylamine, Methyldopa, Moxonidine, Prazosin, Rescinnamine, Reserpine
Vasodilators Diazoxide, Hydralazine, Minoxidil, Nitroprusside, Phentolamine
Other antihypertensives Bosentan, Ketanserin
Low ceiling diuretics Bendroflumethiazide, Chlorothiazide, Chlortalidone, Hydrochlorothiazide, Indapamide, Quinethazone, Mersalyl, Metolazone, Theobromine, Cicletanine
High ceiling diuretics Bumetanide, Furosemide, Torasemide
Potassium-sparing diuretics Amiloride, Eplerenone, Spironolactone, Triamterene
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