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Bill Sikes is a fictional character in the novel Oliver Twist by Charles Dickens

He is one of Dickens's most menacing characters and a very strong force in the novel when it comes to having control over somebody or harming others. He is portrayed as a rough and barbaric man. He is a career criminal associated with Fagin, and an eventual murderer. He is very violent and aggressive, prone to sudden bursts of extreme behaviour. He owns a bull terrier named Bull's Eye, whom he beats until the dog needs stitches.

Dickens describes his first appearance:

The man who growled out these words, was a stoutly-built fellow of about five-and-thirty, in a black velveteen coat, very soiled drab breeches, lace-up half boots, and grey cotton stockings which inclosed a bulky pair of legs, with large swelling calves;--the kind of legs, which in such costume, always look in an unfinished and incomplete state without a set of fetters to garnish them. He had a brown hat on his head, and a dirty belcher handkerchief round his neck: with the long frayed ends of which he smeared the beer from his face as he spoke. He disclosed, when he had done so, a broad heavy countenance with a beard of three days' growth, and two scowling eyes; one of which displayed various parti-coloured symptoms of having been recently damaged by a blow.

His prostitute girlfriend Nancy tolerates his violent and lawless behaviour, perhaps because she, being a thief since the age of six, needs stability in her life, and because she believes that she loves him. When Sikes murders Nancy, thinking she has betrayed him, a mob hounds him through the streets of London until he accidentally hangs himself while trying to escape. The murder is especially gruesome, and is one of the most frightening scenes Dickens ever wrote.

Sikes does have some positive features: for instance, at the robbery in the countryside, Sikes could have left Oliver, but he picks him up and runs with him as far as he can. However, he eventually does abandon the seriously wounded boy and shows absolutely no remorse. In addition, after Sikes kills Nancy, he apparently does feel guilty, although it could be argued that this is merely fear of the possibility of being caught. Sikes lives in Bethnal Green and later moves to the squalid rookery area of London then called Jacob's Island, east of present-day Shad Thames.

Bill Sikes sometimes has his name spelled Bill Sykes; it is unclear which spelling is correct according to Mr. Dickens.^{[citation needed]} In the musical Oliver! his name is spelled Sikes.

Bill Sikes was played by Robert Newton in David Lean's 1948 film of Oliver Twist, and by Oliver Reed in the 1968 film version of Oliver!. In Disney's 1988 film Oliver and Company, the character Sykes (who is loosely based on Bill Sikes) is voiced by Robert Loggia. In the 1999 British television mini-series, he is played by Andy Serkis. In the 2005 film by Roman Polanski, he is played by Jamie Foreman. In the 2007 BBC series of Oliver Twist he is played by Tom Hardy.