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Blanche of Anjou (1280 – October 14, 1310) was the second Queen consort of James II of Aragon.

She was the second daughter of Charles II of Naples and Maria Arpad of Hungary.

Her paternal grandparents were Charles I of Sicily and Beatrice of Provence. Her maternal grandparents were Stephen V of Hungary (d. 1272) and his wife, queen Elisabeth, who was daughter of Zayhan of Kuni, a chief of the Cuman tribe and had been a pagan before her marriage.

On 29 October 1295, Blanche married James II of Aragon. They had ten children:

• James (Jaume) (b. 29 September 1296 - d. Tarragona, July 1334). James renounced his right to the throne in 1319 to become a monk. He refused to consummate his marriage to Leonor of Castille, who later become the second wife of his brother Alfonso.

• Alfonso IV of Aragon (1299 – 24 January 1336). He became the King of Aragon in 1327 and ruled until his death. He married twice: first to Teresa d'Entença and then to Eleanor of Castile after his first wife died.

• Maria (b. 1299 - d. as a nun in Sijena, 1316). She married Pedro of Castile, son of Sancho IV of Castile.

• Constance (Constança) (b. Valencia, 1 April 1300 - d. Castillo de Garcia Munoz, 19 September 1327). Constance married Juan Manuel, Duke of Penafiel, nephew of Alfonso X of Castile.

• John (Juan) (b. 1304 - d. Pobo, Zaragoza, 19 August 1334). John became the first Archbishop of Toledo and Tarragona in 1318, and Patriarch of Alexandria in 1328.

• Isabel of Aragon (b. 1305 - d. Styria, 12 July 1330). Elizabeth married Frederick I of Austria.

• Peter (Pere) (b. 1305 - d. Pisa, 4 November 1381), Count of Ribagorça and Prades. Peter married Jeanne, daughter of Gaston I of Foix.

• Blanca (b. 1307 - d. Barcelona, 1348), Prioress of Sixena.

• Ramon Berenguer (b. August 1308 - d. a priest at Barcelona, 1366), Count of Empúries and Baron of Ejerica.. Ramon married firstly with Blanca, daughter of Philip I of Taranto, and secondly with Maria, daughter of Jaime of Aragon.

• Violante (b. Barcelona, October 1310 - d. Pedrola, 19 July 1353). She first married Philip, Despot of Romania, son of Philip I of Taranto. Her second marriage was with Lope de Luna, Lord of Segorbe.

Preceded by Isabella of Castile	Queen consort of Sicily 1295–1296	Succeeded by Eleanor of Anjou
Preceded by Isabella of Castile	Queen consort of Aragon 1295–1310	Succeeded by Maria of Lusignan
	Countess consort of Barcelona 1295–1310
	Queen consort of Valencia 1295–1310