Bordetella parapertussis

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How to read a taxobox
Bordetella parapertussis
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Beta Proteobacteria
Order: Burkholderiales
Family: Alcaligenaceae
Genus: Bordetella
Species: B. parapertussis
Binomial name
Bordetella parapertussis
(Eldering and Kendrick 1938)
Moreno-López 1952

Bordetella parapertussis is a small Gram-negative bacterium of the genus Bordetella which is adapted to colonise the mammalian respiratory tract.[1] Pertussis caused by B. parapertussis manifests with similar symptoms to B. pertussis-derived disease but tends to be generally less severe.[2]

Two lineages of B. parapertussis have been described. The first infects humans and is responsible for a minority of cases of the disease pertussis (also known as whooping cough).[3] The second, ovine, lineage causes chronic non-progressive pneumonia in sheep.[4] Both lineages are thought to have evolved from a B. bronchiseptica-like ancestor.[5] This disease can be symptomatic or asymptomatic and may predispose hosts to secondary infection.[6]

  1. ^ Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology, 4th ed., McGraw Hill. ISBN 0838585299. 
  2. ^ Heininger U, Stehr K, Schmitt-Grohé S, Lorenz C, Rost R, Christenson P, Uberall M, Cherry J (1994). "Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis". Pediatr Infect Dis J 13 (4): 306-9. PMID 8036048. 
  3. ^ Cherry J (1996). "Historical review of pertussis and the classical vaccine". J Infect Dis 174 Suppl 3: S259-63. PMID 8896526. 
  4. ^ Porter J, Connor K, Donachie W (1994). "Isolation and characterization of Bordetella parapertussis-like bacteria from ovine lungs". Microbiology 140 ( Pt 2): 255-61. PMID 8180690. 
  5. ^ van der Zee A, Mooi F, Van Embden J, Musser J (1997). "Molecular evolution and host adaptation of Bordetella spp.: phylogenetic analysis using multilocus enzyme electrophoresis and typing with three insertion sequences". J Bacteriol 179 (21): 6609-17. PMID 9352907. 
  6. ^ Porter J, Connor K, Krueger N, Hodgson J, Donachie W (1995). "Predisposition of specific pathogen-free lambs to Pasteurella haemolytica pneumonia by Bordetella parapertussis infection". J Comp Pathol 112 (4): 381-9. PMID 7593760. 
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