Brimonidine

From Wikipedia, the free encyclopedia

(Redirected from Brimonidine tartrate)
Jump to: navigation, search
Brimonidine
Systematic (IUPAC) name
5-bromo-N- (4,5-dihydro-1H-imidazol-2-yl) quinoxalin-6-amine
Identifiers
CAS number 59803-98-4
ATC code S01EA05
PubChem 2435
DrugBank APRD00034
Chemical data
Formula C11H10BrN5 
Mol. mass 292.135 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism liver primarily
Half life 3 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

B
Legal status

unknown
Routes Ocular, 1 gtt

Brimonidine (bri-MOE-ni-deen ) is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis.

Brimonidine is an alpha2 receptor agonist.

Alpha 2 agonists, through the activation of the Gi GPCR, inhibit the production of AC. This reduces cAMP and hence Aqueous Humour production by the ciliary body.

  • Conjunctivitis
  • Conjunctival hyperemia
  • Ocular pruritus
  • Ocular burning
  • Conjunctival follicles
  • Hypertension
  • Dry mouth
  • Visual changes
  • Somnolence
v • d • e
Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine
Parasympathomimetics Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine
Carbonic anhydrase inhibitors Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide
Beta blocking agents Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol
Prostaglandin analogues Bimatoprost • Latanoprost • Travoprost • Unoprostone
Other agents Dapiprazole • Guanethidine


Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
Retrieved from "http://en.wikipedia.org/wiki/Brimonidine"
Advanced Search
Included Web Search Engines


Safe Search

close

Top Matching Results

Occasionally Search.com will highlight specialized results that are based on the context of your query. Examples of specialized results include specific links to news, images, or video.

Top Matching Results may highlight information from other Search.com pages, content from the CNET Network of sites, or third party content. The listings are based purely on relevance. Search.com does not receive payment for listings in this section but our partners that provide this data may get paid for listing these products.

Sponsored Links

This section contains paid listings which have been purchased by companies that want to have their sites appear for specific search terms and related content. These listings are administered, sorted and maintained by a third party and are not endorsed by Search.com.

Search Results

Search.com sends your search query to several search engines at one time and integrates the results into one list which has been sorted by relevance using Search.com's proprietary algorithm. You can customize the list of search engines included in your metasearch from the preferences.

The search engines that are used in your metasearch may allow companies to pay to have their Web sites included within the results. To view the Paid Inclusion policy for a specific search engine, please visit their Web site. Search.com does not accept payment or share revenue with any search engine partner for listings in this section.