Sources
open directory project
Help build the largest human-edited directory on the web.
Submit a site - Become an editor
Wikipedia. Licensed under the GNU Free Documentation License.
Are you an expert in this subject? Join the discussion and share your knowledge at Wikipedia.org.
Calcidiol
From Wikipedia, the free encyclopedia
(Redirected from 25-hydroxy vitamin D)
| Calcidiol | |
|---|---|
 |
|
| IUPAC name | (6R)-6-[(1R,3aR,4E,7aR)-4-[(2Z)-2-[(5S)-5- Hydroxy-2-methylidene-cyclohexylidene] ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro- 1H-inden-1-yl]-2-methyl-heptan-2-ol |
| Other names | 25-Hydroxyvitamin D3 25-Hydroxycholecalciferol Calcifediol |
| Identifiers | |
| CAS number | |
| PubChem | |
| MeSH | |
| SMILES | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@] 1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C |
| Properties | |
| Molecular formula | C27H44O2 |
| Molar mass | 400.637 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
Calcidiol, calcifediol, 25-hydroxycholecalciferol, or 25–hydroxy–vitamin D, is a prehormone which is produced by the hepatic metabolism (hydroxylation) of vitamin D3 (cholecalciferol) and which is converted by the kidneys (via 25-Hydroxyvitamin D3 1-alpha-Hydroxylase) into calcitriol (1,25-vitamin D), a steroid hormone.
In medicine, bloodstream concentration of calcidiol is commonly used to measure overall vitamin D levels. Calcifediol promotes the mineralization of bones and teeth and is used to treat diseases caused by vitamin D deficiency such as rickets and osteomalacia. It is effective even in azotemic patients.[citation needed]
- Dietary Reference intakes for Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. Institute of Medicine, 1997
- Vitamin D Pharmacology at VitaminDCouncil.com
|
|
|
|---|---|
| fat soluble | A (Retinol, Beta-carotene) - D (Ergocalciferol, Cholecalciferol, Dihydrotachysterol, Calcitriol, Calcidiol) - E (Tocopherol) - K (Naphthoquinone) |
| water soluble: B vitamins | B1 (Thiamine, Sulbutiamine, Benfotiamine) - B2 (Riboflavin) - B3 (Niacin, Nicotinamide) - B5 (Pantothenic acid, Dexpanthenol, Pantethine) - B6 (Pyridoxine, Pyridoxal phosphate) - B7 (Biotin) - B9 (Folic acid) - B12 (Cyanocobalamin, Hydroxocobalamin, Mecobalamin) |
| water soluble: other | C (Ascorbic acid) - Choline |