Calreticulin

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calreticulin
Identifiers
Symbol	CALR
HUGO	1455
Entrez	811
OMIM	109091
RefSeq	NM_004343
UniProt	P27797
Other data
Locus	Chr. 19 p13.3-13.2

Calreticulin is a protein that binds Ca²⁺ ions (a second messenger molecule in signal transduction), rendering it inactive. The Ca²⁺ is bound with low affinity, but high capacity, and can be released on a signal (see inositol triphosphate). Calreticulin is located in storage compartments associated with the endoplasmic reticulum.

Calreticulin is also known as calregulin, CRP55, CaBP3 and calsequestrin-like protein.

Calreticulin binds to misfolded proteins and prevents them from being exported from the Endoplasmic reticulum to the Golgi apparatus.

MeSH Calreticulin

Links to external chemical sources

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v • d • e

Carrier protein: calcium-binding proteins

Annexin (A1, A2, A5) - Vitamin D-dependent calcium-binding protein/Calbindin - Calexcitin - Calsequestrin - Osteocalcin - Osteonectin - S-100 - Synaptotagmin - Troponin C

Intracellular calcium-sensing proteins: Calmodulin - Calnexin - Calreticulin - Gelsolin - neuronal (Hippocalcin, Neurocalcin, Recoverin)

v • d • e

Protein: lectins

animal: Calnexin - Calreticulin - CD22 - CD33 - Galectin - Mannan-binding lectin - Myelin-associated glycoprotein - N-Acetylglucosamine receptor - Selectin - Sialoadhesin
animal, calcium-dependent: Aggrecan - Asialoglycoprotein receptor - CD94 - Collectin - Mannose receptor - Versican

plant: Abrin - Concanavalin A - Phytohaemagglutinin - Pokeweed mitogen - Ricin

Retrieved from "http://en.wikipedia.org../../../c/a/l/Calreticulin.html"

Categories: Protein pages needing a picture | Genes on chromosome 19 | Biochemistry | Immune system | Proteins | Protein stubs

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