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Cicletanine
From Wikipedia, the free encyclopedia
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Cicletanine
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| Systematic (IUPAC) name | |
| 3-(4-Chloro-phenyl)-6-methyl-1,3-dihydro-furo[3,4-c]pyridin-7-ol | |
| Identifiers | |
| CAS number | |
| ATC code | C03 |
| PubChem | |
| Chemical data | |
| Formula | C14H12ClNO2 |
| Mol. mass | 261.703 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 97.3% |
| Metabolism | ? |
| Half life | 7.9 h |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
Cicletanine is a furopyridine low-ceiling diuretic drug, usually used in the treatment of hypertension.[1] The drug is manufactured by Ipsen and marketed by Recordati (in France) under the trade name Tenstaten®.
- ^ Jean Sassard (1992), Genetic Hypertension, John Libbey Eurotext, ISBN 086196313X
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| Antiadrenergic agents (including alpha) | Clonidine, Doxazosin, Guanethidine, Guanfacine, Lofexidine,Mecamylamine, Methyldopa, Moxonidine, Prazosin, Rescinnamine, Reserpine |
| Vasodilators | Diazoxide, Hydralazine, Minoxidil, Nitroprusside, Phentolamine |
| Other antihypertensives | Bosentan, Ketanserin |
| Low ceiling diuretics | Bendroflumethiazide, Chlorothiazide, Chlortalidone, Hydrochlorothiazide, Indapamide, Quinethazone, Mersalyl, Metolazone, Theobromine, Cicletanine |
| High ceiling diuretics | Bumetanide, Furosemide, Torasemide |
| Potassium-sparing diuretics | Amiloride, Eplerenone, Spironolactone, Triamterene |
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