Demecarium bromide

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Demecarium bromide
Systematic (IUPAC) name
trimethyl-[3-[methyl-[10-[methyl- (3-trimethylammoniophenoxy) carbonyl-amino] decyl] carbamoyl] oxyphenyl]-ammonium dibromide
Identifiers
CAS number 56-94-0
ATC code S01EB04
PubChem 5965
DrugBank APRD00905
Chemical data
Formula C32H52Br2N4O4 
Mol. mass 716.588 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?
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Demecarium bromide is a compound classified by the World Health Organization as a parasympathomimetic.[citation needed]

  • Ward D, Abney K, Oliver J (2003). "The effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase levels in normal dogs.". Vet Ophthalmol 6 (1): 23-5. PMID 12641839. 
  • Krohne S (1994). "Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs.". Am J Vet Res 55 (12): 1729-33. PMID 7887518. 
  • Gum G, Gelatt K, Gelatt J, Jones R (1993). "Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma.". Am J Vet Res 54 (2): 287-93. PMID 8430939. 
v • d • e
Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine
Parasympathomimetics Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine
Carbonic anhydrase inhibitors Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide
Beta blocking agents Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol
Prostaglandin analogues Bimatoprost • Latanoprost • Travoprost • Unoprostone
Other agents Dapiprazole • Guanethidine


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