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This article is about the ecological meaning of "endemic". See also endemic (epidemiology).

Endemism is the ecological state of being unique to a place. Endemic species are not naturally found elsewhere. The place must be a discrete geographical unit, such as an island, habitat type, or other defined area or zone. For example, the Orange-breasted Sunbird is endemic to Fynbos, meaning it is exclusively found in the Fynbos vegetation type of southwestern South Africa.

An opposite notion is cosmopolitan distribution.

Endemic types or species are especially likely to develop on islands due to their geographical isolation. This includes remote island groups, such as Hawaii, the Galápagos Islands and Socotra. Endemism can also occur in biologically isolated areas such as the highlands of Ethiopia, or large bodies of water like Lake Baikal.

Endemics can easily become endangered or extinct due to their restricted habitat and vulnerability to the actions of man, including the introduction of new organisms. There were millions of both petrels and "cedars" (actually junipers) in Bermuda when it was settled at the start of the 17th century. By the end of the century, the petrels were thought to be extinct, and cedars were driven nearly to extinction. This was caused by centuries of shipbuilding as well as the introduction of a parasite. Both petrels and cedars are very rare today, as are other species endemic or native to Bermuda.

Endemic organisms are not the same as indigenous organisms — a species that is indigenous to somewhere may be native to other locations as well. An introduced species, also known as a naturalized or exotic species, is an organism that is not indigenous to a given place or area.

According to the World Wildlife Fund, the following ecoregions have the highest percentage of endemic plants:

• Fynbos (South Africa)
• Hawaii dry forests (United States)
• Hawaii tropical moist forests (United States)
• Kwongan heathlands (Australia)
• Madagascar dry deciduous forests (Madagascar)
• Madagascar lowland forests (Madagascar)
• New Caledonia dry forests (New Caledonia)
• New Caledonia rain forests (New Caledonia)
• Sierra Madre de Oaxaca and Sierra Madre del Sur pine-oak forests (Mexico, Guatemala)

Some of the principal threats to these special ecosystems are:

• Global warming
• Large scale logging operations
• Slash-and-burn techniques sometimes a part of shifting cultivation

The above factors are secondary results of world overpopulation.

• Endemism in birds
• Biodiversity hotspot
• Endemic Maltese Wildlife
• Floristic province