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Factor B
From Wikipedia, the free encyclopedia
(Redirected from BF in immunology)
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complement factor B
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| Identifiers | |
| Symbol | CFB |
| Alt. Symbols | BFD, BF |
| Entrez | 629 |
| HUGO | 1037 |
| OMIM | 138470 |
| RefSeq | NM_001710 |
| UniProt | P00751 |
| Other data | |
| EC number | 3.4.21.47 |
| Locus | Chr. 6 p21.3 |
Factor B is a protein involved in the alternative complement pathway of the complement system.
It binds C3H2O, and is then cleaved by Factor D into Ba and Bb.
- {{MeshName|Complement+
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| Activators | CLA: C3-convertase - MAC (C6, C7, C8, C9) - L: Mannan-binding lectin - A: Factor P/Properdin |
| Enzymes | C: C1Q/C1R/C1S - C4 - C2 - CLA: C3 - C5 (C5a) - L: MASP1 - MASP2 - A: Factor B - Factor D |
| Inhibitors | CLA: C1-inhibitor - Decay accelerating factor - Factor I - CL: C4BP - A: Factor H |
| Complement receptors | CR1 - CR2 - CR3 - CR4 - CD11b/CD11c/CD18 - Anaphylatoxin (C3a, C5a) |
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| Digestive system | Enteropeptidase - Trypsin - Chymotrypsin - Elastase (Neutrophil, Pancreatic) |
| Complement system | Factor B - Factor D - Factor I - MASP (MASP1, MASP2) - C3-convertase |
| Coagulation | factors: Thrombin - Factor VIIa - Factor IXa - Factor Xa - Factor XIa - Factor XIIa - Kallikrein (PSA) fibrinolysis: Plasmin - Tissue plasminogen activator - Urinary plasminogen activator |
| Immune system | Chymase - Granzyme - Tryptase - Proteinase 3/Myeloblastin |
| Venombin | Ancrod - Batroxobin |
| Other | Acrosin - Prolyl endopeptidase - Pronase - Proprotein convertases (1, 2) - Subtilisin/Furin - Streptokinase - S1P |
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