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Fournier gangrene
From Wikipedia, the free encyclopedia
| ICD-10 | N49.8 (ILDS N49.81), N76.8 |
|---|---|
| ICD-9 | 608.83 |
| DiseasesDB | 31119 |
| eMedicine | emerg/929 med/2814 |
| MeSH | D018934 |
Fournier gangrene is a type of necrotizing infection (gangrene) usually affecting the male genitals. It is a type of necrotizing fasciitis.
It was first described by Baurienne in 1764 and is named after a French venereologist, Jean-Alfred Fournier following five cases he presented in clinical lectures in 1883.
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In the majority of cases Fournier gangrene is a mixed infection caused by both aerobic and anaerobic bacteria.[1]
Only 600 cases of Fournier gangrene were reported in the world literature in the ten years since 1996, with most patients in their 60s or 70s with other concurrent illnesses.[2] However, Fournier's gangrene is not a reportable illness, and the condition is not uncommon, especially among diabetic individuals. A similar infection in women has been occasionally described.[3]
In Turkey it was reported that 46% of patients had diabetes mellitus[4] whilst other studies have identified approximately a third of patients having either diabetes, alcoholism or malnutrition, and 10% having medical immunosuppression (chemotherapy, steroids, malignancy).[5]
Fournier gangrene is a urological emergency requiring intravenous antibiotics and debridement (surgical removal) of necrotic (dead) tissue. Despite such measures, the mortality rate overall is 40%, but 78% if sepsis is already present at the time of initial hospital admission.[4]
- ^ Thwaini A, Khan A, Malik A, Cherian J, Barua J, Shergill I, Mammen K (2006). "Fournier's gangrene and its emergency management". Postgrad Med J 82 (970): 516-9. PMID 16891442.
- ^ Vaz I (2006). "Fournier gangrene". Trop Doct 36 (4): 203-4. PMID 17034687.
- ^ Herzog W (1987). "[Fournier gangrene--also in females?]". Zentralbl Chir 112 (9): 564-76. PMID 2956804.
- ^ a b Yanar H, Taviloglu K, Ertekin C, Guloglu R, Zorba U, Cabioglu N, Baspinar I (2006). "Fournier's gangrene: risk factors and strategies for management". World J Surg 30 (9): 1750-4. PMID 16927060.
- ^ Tahmaz L, Erdemir F, Kibar Y, Cosar A, Yalcýn O (2006). "Fournier's gangrene: report of thirty-three cases and a review of the literature". Int J Urol 13 (7): 960-7. PMID 16882063.