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Fumarase
From Wikipedia, the free encyclopedia
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fumarate hydratase
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| Identifiers | |
| Symbol | FH |
| HUGO | 3700 |
| Entrez | 2271 |
| OMIM | 136850 |
| RefSeq | NM_000143 |
| UniProt | P07954 |
| Other data | |
| EC number | 4.2.1.2 |
| Locus | Chr. 1 q42.1 |
Fumarase (or fumarate hydratase) is an enzyme involved in the Krebs Cycle (aka the Tricarboxylic Acid Cycle aka the Citric Acid Cycle) that catalyzes the hydration (addition of H2O across a double bond) of Fumarate to L-malate (See the entry on optical isomer).
Fumarate <-> L Malate + H2O
- Diagram TCA Cycle at KEGG, gives some details on the TCA cycle in which fumerase acts. [Fumarase is labeled '4.2.1.2' in the lower left hand corner of this diagram.
- [Crystal structure of Yeast Fumarase] at the Protein Data Bank.
- MeSH Fumarase
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