Glucocerebrosidase

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Acid β-glucosidase, drawn from PDB 1OGS.
glucosidase, beta; acid (includes glucosylceramidase)
Identifiers
Symbol	GBA GLUC
HUGO	4177
Entrez	2629
OMIM	606463
RefSeq	NM_000157
UniProt	P04062
Other data
EC number	3.2.1.21
Locus	Chr. 1 q22

Glucocerebrosidase (also called glucosylceramidase or D-glucosyl-N-acylsphingosine glucohydrolase) is an enzyme (EC 3.2.1.45) that is needed to break down the chemical glucocerebroside by hydrolysis. It is localized in the lysosome and has a molecular weight of 59700 Daltons. It is the enzyme that is defective in cells of patients with Gaucher disease.

MeSH Glucocerebrosidase

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v • d • e

Hydrolase: sugar hydrolases (EC 3.2)

Glycoside hydrolases: Amylase - Cellulase - Chitinase - Disaccharidase (Lactase, Maltase, Sucrase, Trehalase) - Galactosidases (Alpha, Beta) - Galactosylceramidase - Glucocerebrosidase - Glucuronidase - Hexosaminidase - Hyaluronidase - Iduronidase - Lysozyme - alpha-Mannosidase - Neuraminidase

DNA glycosylases: Oxoguanine glycosylase

Retrieved from "http://en.wikipedia.org../../../g/l/u/Glucocerebrosidase.html"

Categories: Genes on chromosome 1 | EC 3.2.1 | Enzyme stubs

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