Histidine decarboxylase

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histidine decarboxylase
Identifiers
Symbol HDC
Entrez 3067
HUGO 4855
OMIM 142704
RefSeq NM_002112
UniProt P19113
Other data
EC number 4.1.1.22
Locus Chr. 15 q21-q22

Histidine decarboxylase (HDC) is the enzyme that catalyzes the reaction which produces histamine from histidine as follows:

C6H9N3O2 → C5H9N3 + CO2

Conversion of histidine to histamine by histidine decarboxylase
Conversion of histidine to histamine by histidine decarboxylase

 This lyase article is a stub. You can help Wikipedia by expanding it.
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Carbon-carbon lyases (EC 4.1)
4.1.1: Carboxy-lyases Pyruvate decarboxylase -Oxaloacetate decarboxylase - Acetoacetate decarboxylase - Malonyl-CoA decarboxylase - Glutamate decarboxylase - Ornithine decarboxylase - Lysine decarboxylase - Phosphoribosylaminoimidazole carboxylase - Histidine decarboxylase - Uridine monophosphate synthetase/Orotidine 5'-phosphate decarboxylase - Aromatic L-amino acid decarboxylase - Phosphoenolpyruvate carboxylase - Pyrophosphomevalonate decarboxylase - Uroporphyrinogen III decarboxylase - RuBisCO - Phosphoenolpyruvate carboxykinase - Adenosylmethionine decarboxylase
4.1.2: Aldehyde-lyases Aldolase A/Aldolase B - 2-hydroxyphytanoyl-CoA lyase
4.1.3: Oxo-acid-lyases 3-hydroxy-3-methylglutaryl-CoA lyase
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Amino acid metabolism enzymes
phenylalanine→tyrosine→fumarate→TCA Phenylalanine hydroxylase - Tyrosine aminotransferase - 4-Hydroxyphenylpyruvate dioxygenase - Homogentisate 1,2-dioxygenase - Fumarylacetoacetate hydrolase
tyrosine→dopamine→epinephrine Tyrosine hydroxylase - Aromatic L-amino acid decarboxylase - Dopamine beta hydroxylase - Phenylethanolamine N-methyltransferase
leucine→HMG-CoA (keto) Branched-chain alpha-keto acid dehydrogenase complex - Isovaleryl coenzyme A dehydrogenase - Methylcrotonyl-CoA carboxylase
isoleucine/valine→propionyl-CoA Branched-chain alpha-keto acid dehydrogenase complex
methionine→cysteine→propionyl-CoA Methionine adenosyltransferase - Adenosylhomocysteinase - (or MTR) - Cystathionine beta synthase - Cystathionine gamma-lyase
propionyl-CoA→succinyl-CoA→TCA Propionyl-CoA carboxylase - Methylmalonyl-CoA mutase
serine→glycine Serine hydroxymethyltransferase
histidine to histamine: Histidine decarboxylase - to glutamate: Histidine ammonia-lyase - Urocanate hydratase - Formiminotransferase cyclodeaminase
tryptophan→serotonin→melatonin Tryptophan hydroxylase - Aromatic L-amino acid decarboxylase - 5-hydroxyindole-O-methyltransferase
asparagine→aspartate→oxaloacetate→TCA Asparaginase/Asparagine synthetase - Aspartate transaminase
glutamate Glutaminase - Glutamate decarboxylase
lysine→keto Saccharopine dehydrogenase
other Tyrosinase
Retrieved from "http://en.wikipedia.org/wiki/Histidine_decarboxylase"
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