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Homatropine
From Wikipedia, the free encyclopedia
(Redirected from Equipin)
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Homatropine
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| Systematic (IUPAC) name | |
| (8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl) 2-hydroxy-2-phenyl-acetate bromide | |
| Identifiers | |
| CAS number | |
| ATC code | A02 S01FA05 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C17H24BrNO3 |
| Mol. mass | 370.28 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Homatropine (Equipin®, Isopto Homatropine®) is an anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic, to temporarily paralyze accommodation, and as a mydriatic, to dilate the pupil.
Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide or methylbromide salt.
Drugs like hydrocodone are mixed with small amounts of an anticholinergic such as homatropine methylbromide to discourage abuse.
Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administation.
- Blurred vision
- Sensitivity to light
- Untreated glaucoma
- Myasthenia gravis
- Severe heart failure
- Thyrotoxicosis
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This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
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| Anticholinergics/antimuscarinics | Atropine - Scopolamine - Methylscopolamine - Cyclopentolate - Homatropine - Tropicamide |
| Sympathomimetics | Phenylephrine - Ephedrine - Ibopamine |