Howard Hughes Medical Institute

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Coordinates: 38°59′55.00″N, 77°04′45.00″W

Howard Hughes Medical Institute
Howard Hughes Medical Institute Logo
Founder Howard Hughes
Founded 1953
Headquarters Chevy Chase, Maryland, United States
Focus Biological and Medical research and Science Education
Method Laboratories, Funding
Endowment $16.3 billion USD
Website [1]

The Howard Hughes Medical Institute (HHMI) is a United States non-profit medical research institute based in ng in the late 1950s it began funding 47 investigators researching at eight different institutions; however, it remained a modest enterprise for several decades. In fact it was not until after Hughes' death in 1976 that the Institute's profile increased from an annual budget of $4 million in 1975 to $15 million by 1978. In this period it refocused its mission on genetics, immunology and the rapidly growing field of molecular biology. Since Hughes died without a will as the sole trustee of the HHMI, the Institute was involved in lengthy court proceedings to determine whether it would benefit from Hughes fortune. In April 1984, a court appointed new trustees for the institute's holdings. (The original trustees are: Helen K. Copley, Donald S. Frederickson, M.D., Frank William Gay, James H. Gilliam, Jr., Esq., Hanna H. Gray, Ph.D., William R. Lummis, Esq., Irving S. Shapiro, Esq., George W. Thorn, M.D.) In January 1985 the trustees announced they would sell Hughes Aircraft either by private sale or public stock offering. On June 5, 1985 General Motors was announced as the winner of a secretive five month, sealed-bid auction. The purchase was completed on December 20, 1985 for an estimated $5.2 billion, $2.7 billion in cash and the rest in 50 million shares of GM Class H stock. The proceeds caused the institute to grow dramatically.

HHMI has recently completed building a new research campus in Ashburn, Virginia called Janelia Farm Research Campus. It is modeled after AT&T's Bell Labs and the Medical Research Council's Laboratory of Molecular Biology. With a main laboratory building nearly 1,000 feet long, it contains 760,000 square feet of enclosed space, used primarily for research. The campus also features apartments for visiting researchers.

In 2007, HHMI and the publisher Elsevier announced that they have established an agreement to make author manuscripts of HHMI research articles published in Elsevier and Cell Press journals publicly available six months following final publication. The agreement takes effect for articles published after September 1, 2007.

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