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The Infrared Processing and Analysis Center (IPAC) is the NASA science center which is responsible for the data processing, analysis, and archiving for NASA's infrared astronomy and astrophysics missions. It is located on the campus of the California Institute of Technology

IPAC was established in 1986 to provide support for the joint European-American orbiting infrared telescope, the Infrared Astronomical Satellite, or IRAS. The IRAS mission performed an unbiased, sensitive all-sky survey at 12, 25, 60 and 100 µm during 1983, and after the mission ended, IPAC started the Infrared Science Archive (IRSA) to make the data available to anyone who needed it.

Later, NASA designated IPAC as the U.S. science support center for the European Infrared Space Observatory (ISO), which ceased operations in 1998. About that same time, IPAC was designated as the science center for the Space Infrared Telescope Facility (SIRTF) -- renamed the Spitzer Space Telescope after launch. IPAC also assumed the lead role in various other infrared space missions, including the Wide-field Infrared Explorer (WIRE) and the Midcourse Space Experiment (MSX). IPAC also expanded its support to include ground-based missions with the assumption of science support responsibilities for the Two-Micron All-Sky Survey (2MASS), a near-infrared survey of the entire sky conducted by twin observatories in the Northern and Southern hemispheres.

In 1999, IPAC formed an interferometry science center, ultimately named the Michelson Science Center after interferometry pioneer Albert A. Michelson.

Today, the greater IPAC includes the Spitzer Science Center, the Michelson Science Center, the NASA Herschel Science Center, and supports over a dozen different science missions.

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