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Lercanidipine
From Wikipedia, the free encyclopedia
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Lercanidipine
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| Systematic (IUPAC) name | |
| methyl[2-(3,3-diphenylpropyl-methyl-amino)- 1,1-dimethyl-ethyl] 2,6-dimethyl- 4-(3-nitrophenyl)- 1,4-dihydropyridine-3, 5-dicarboxylate | |
| Identifiers | |
| CAS number | |
| ATC code | C08 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C36H41N3O6 |
| Mol. mass | 611.727 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
It is sold under various commerical names including Zanidip.
- Lin T, Voon W, Yen H, Huang C, Su H, Lai W, Sheu S (2006). "Lercanidipine and losartan effects on blood pressure and fibrinolytic parameters.". Kaohsiung J Med Sci 22 (4): 177-83. PMID 16679299.
- Martinez M, Lopes L, Coelho E, Nobre F, Rocha J, Gerlach R, Tanus-Santos J (2006). "Lercanidipine reduces matrix metalloproteinase-9 activity in patients with hypertension.". J Cardiovasc Pharmacol 47 (1): 117-22. PMID 16424795.
- Agrawal R, Marx A, Haller H (2006). "Efficacy and safety of lercanidipine versus hydrochlorothiazide as add-on to enalapril in diabetic populations with uncontrolled hypertension.". J Hypertens 24 (1): 185-92. PMID 16331117.
| Calcium channel blockers (C08) | |
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| Dihydropyridines | Amlodipine, Felodipine, Isradipine, Lacidipine, Lercanidipine, Nicardipine, Nifedipine, Nimodipine, Nisoldipine |
| Phenylalkylamines | Verapamil |
| Benzothiazepines | Diltiazem |
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