Medication

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A medicine or drug is any substance or combination of substances administered to human beings or animals to treat or prevent disease; alternatively to assist in medical diagnosis. Medication, a word more widely used to mean the act of administering medicine, is used in the health industry as a synonym for the word "medicine" itself.

Contents

Medication can be usually classified in various ways, e.g. by its chemical properties, mode of administration, or biological system affected. An elaborate and widely used classification system is the Anatomical Therapeutic Chemical Classification System(ATC system). The types of medicines:

1)Antipyretics  : Reducing fever.
2)Analgesics  : Painkillers.
3)Anti-malarial drugs : Treating malaria.
4)Antibiotics  : Inhibiting germ growth.
5)Antiseptics  : Prevention of germ growth near burns,cuts and wounds.

See also: Psychiatric medication

hypnotic, anaesthetics, antipsychotic, antidepressant (including tricyclic antidepressants, monoamine oxidase inhibitor, lithium salt, selective serotonin reuptake inhibitor), anti-emetic, anticonvulsant and antiepileptic, anxiolytic, barbiturate, movement disorder drug, stimulant (including amphetamines), benzodiazepine, cyclopyrrolone, dopamine antagonist, antihistamine, cholinergic, anticholinergic, emetic, cannabinoids, 5-HT antagonist

Further information: Analgesic

The main classes of painkillers are NSAIDs, opioids and various orphans such as paracetamol, tricyclic antidepressants and anticonvulsants.

NSAIDs (including COX-2 selective inhibitors), muscle relaxant, neuromuscular drug
anticholinesterase

sympathomimetic, antihistamine, anticholinergic, NSAIDs, steroid, antiseptic, local anesthetic, antifungal, cerumenolyti

bronchodilator, NSAIDs, anti-allergic, antitussive, mucolytic, decongestant
corticosteroid, beta-receptor antagonist, anticholinergic, steroid

androgen, antiandrogen, gonadotropin, corticosteroid, growth hormone, insulin, antidiabetic (sulfonylurea, biguanide/metformin, thiazolidinedione, insulin), thyroid hormones, antithyroid drugs, calcitonin, diphosponate, vasopressin analogues

antifungal, alkalising agent, quinolones, antibiotic, cholinergic, anticholinergic, anticholinesterase, antispasmodic, 5-alpha reductase inhibitor, selective alpha-1 blocker, sildenafil

NSAIDs, anticholinergic, haemostatic drug, antifibrinolytic, Hormone Replacement Therapy, bone regulator, beta-receptor agonist, follicle stimulating hormone, luteinising hormone, LHRH
gamolenic acid, gonadotropin release inhibitor, progestogen, dopamine agonist, oestrogen, prostaglandin, gonadorelin, clomiphene, tamoxifen, Diethylstilbestrol

emollient, anti-pruritic, antifungal, disinfectant, scabicide, pediculicide, tar products, vitamin A derivatives, vitamin D analogue, keratolytic, abrasive, systemic antibiotic, topical antibiotic, hormones, desloughing agent, exudate absorbent, fibrinolytic, proteolytic, sunscreen, antiperspirant, corticosteroid

antibiotic, antifungal, antileprotic, antituberculous drug, antimalarial, anthelmintic, amoebicide, antiviral, antiprotozoal

vaccine, immunoglobulin, immunosuppressant, interferon, monoclonal antibody

anti-allergic, antihistamine, NSAIDs

tonic, iron preparation, electrolyte, parenteral nutritional supplement, vitamins, anti-obesity drug, anabolic drug, haematopoietic drug, food product drug

cytotoxic drug, sex hormones, aromatase inhibitor, somatostatin inhibitor, recombinant interleukins, G-CSF, erythropoietin

contrast media

A euthanaticum is used for euthanasia and physician-assisted suicide, see also barbiturates.

Euthanasia is not permitted by law in many countries, and consequently medicines will not be licenesed for this use in those countries.

Medications may be divided into over-the-counter drugs (OTC) which may be available without special restrictions, and prescription only medicine (POM), which must be prescribed by a licensed medical practitioner. The precise distinction between OTC and prescription depends on the legal jurisdiction.

The International Narcotics Control Board of the United Nations imposes a world law of prohibition of certain medications. They publish a lengthy list of chemicals and plants whose trade and consumption (where applicable) is forbidden. OTC medications are sold without restriction as they are considered safe enough that most people will not hurt themselves accidentally by taking it as instructed. Many countries, such as the United Kingdom have a third category of pharmacy medicines which can only be sold in registered pharmacies, by or under the supervision of a pharmacist.

Polypharmacy: suggests that multiple use of prescribed and non-prescribed medications, (use of 5 or more), can have adverse effects on the recipient.

Zoopharmacognosy: Animal usage of drugs and non-foods.

A blockbuster drug is a drug generating more than $1 billion of revenue for its owner each year. The search for blockbusters has been the foundation of the R&D strategy adopted by big pharmaceutical companies, but this looks set to change. New advances in genomics, and the promise of personalized medicine, are likely to fragment the pharmaceutical market.

A recent report from Urch Publishing estimated that about one third of the pharma market by value is accounted for by blockbusters. About 100 products are blockbusters. The top seller was Lipitor a cholesterol-lowering medication marketed by Pfizer with sales of $12.2 billion.

Medication Trade name Company Sales[1] [2] (billion $), year
atorvastatin Lipitor Pfizer 5.9 <
clopidogrel Plavix Bristol-Myers Squibb and sanofi-aventis 5.9 2005
enoxaparin Lovenox or Clexane sanofi-aventis
celecoxib Celebrex Pfizer
omeprazole Losec/Prilosec AstraZeneca 2.6 2004
esomeprazole Nexium AstraZeneca 3.3 2003
Fexofenadine Telfast/Allegra Aventis 1.87 2004
quetiapine Seroquel AstraZeneca 1.5 2003
metoprolol Seloken/Toprol AstraZeneca 1.3 2003
budesonide Pulmicort/Rhinocort AstraZeneca 1.3 2003 (plus some fraction of the $0.6bn sales of Symbicort)

  1. ^ Pharmaceutical Market Trends, 2006-2010, from Urch Publishing [1]
  2. ^ Blockbuster Drugs 2006: Executive Overview, from Report Buyer[2]

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