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One of the key concerns of older adults is the experience of memory loss, especially as it is one of the hallmark symptoms of Alzheimer's disease. However, memory loss is qualitatively different in normal aging from the kind of memory loss associated with a diagnosis of Alzheimer's (Budson & Price, 2005).

Recent research has identified a transitional state between the cognitive changes of normal aging and Alzheimer's disease (AD), known as mild cognitive impairment (MCI). Many people that experience mild cognitive impairment are at a high risk of developing Alzheimer’s disease. Several studies have indicated that MCI individuals are at an increased risk for developing AD, ranging from 1% to 25% per year; 24% of MCI patients progressed to AD in 2 years and 20% more over 3 years, whereas a recent study indicated that the progression of MCI subjects was 55% in 4.5 years (Almkvist & Arnáiz, 2003).

The ability to encode new memories of events or facts and working memory shows decline in both cross-sectional and longitudinal studies (Hedden & Gabrieli, 2004). Studies comparing the effects of aging on episodic memory, semantic memory, short-term memory and priming find that episodic memory is especially impaired in normal aging (Nilsson, 2003). These deficits may be related to impairments seen in the ability to refresh recently processed information (Johnson et al., 2002). In addition, even when equated in memory for a particular item or fact, older adults tend to be worse at remembering the source of their information (Johnson, Hashtroudi, & Lindsay, 1993), a deficit that may be related to declines in the ability to bind information together in memory (Mitchell et al., 2000).

In contrast, implicit, or procedural memory typically shows no decline with age (Fleischman et al., 2004), short-term memory shows little decline (Nilsson, 2003) and semantic knowledge, such as vocabulary, actually improves somewhat with age (Verhaeghen, 2003). In addition, the enhancement seen in memory for emotional events is also maintained with age (Mather & Carstensen, 2005).

Memory is involved in remembering to do things in the future, as well as in remembering what happened in the past. Some studies have found that older adults are worse at prospective memory than younger adults are, yet studies that examine prospective memory in naturalistic contexts often find that older adults are better than younger adults (Henry et al., 2004).

Most research on memory and aging has focused on how older adults perform less well at a particular memory task. However, recently researchers have also discovered that simply saying that older adults are doing the same thing, only less of it, is not always accurate. In some cases, older adults seem to be using different strategies than younger adults. For example, brain imaging studies have revealed that older adults are more likely to use both hemispheres when completing memory tasks than younger adults (Cabeza, 2002). In addition, older adults sometimes show a positivity effect when remembering information, which seems to be a result of the increased focus on regulating emotion seen with age (Mather & Carstensen, 2005). For instance, eye tracking reveals that older adults showed preferential looking toward happy faces and away from sad faces (Isaacowitz, Wadlinger, Goren & Wilson, 2006).

• Aging
• Brain aging
• Childhood amnesia
• Cognitive enhancement
• Life extension
• List of life extension related topics
• Memory

• Almkvist, O., & Arnáiz, E. (2003). Neuropsychological features of mild cognitive impairment and preclinical Alzheimer's disease.
• Budson A.E., & Price B.H. (2005). Memory Dysfunction. The New England Journal of Medicine, 352, 692-699.
• Cabeza, R. (2002). Hemispheric asymmetry reduction in older adults: The HAROLD model. Psychology and Aging, 17, 85-100.
• Fleischman, D.A., Wilson, R.S., Gabrieli, J.D.E., Bienias, J.L., Bennett, D.A. (2004). Abstract A longitudinal study of implicit and explicit memory in old persons. Psychology and Aging, 19, 617-625.
• Hedden, T., & Gabrieli, J.D.E. (2004). Insights into the ageing mind: A view from cognitive neuroscience. Nature Reviews Neuroscience, 5, 87-97.
• Henry, J.D., MacLeod, M.S., Phillips, L.H., & Crawford, J.R. (2004). "A meta-analytic review of prospective memory and aging". Psychology and Aging, 19, 27-39.
• Isaacowitz D. M., Wadlinger H. A., Goren D., et al.(2006). Selective preference in visual fixation away from negative images in old age? An eye tracking study. Psychology and Aging, 21, 40-48.
• Johnson, M.K., Hashtroudi, S., & Lindsay, D.S. (1993). Source monitoring. Psychological Bulletin, 114, 3-28.
• Johnson, M.K., Reeder, J.A., Raye, C.L., & Mitchell, K.J. (2002). Second thoughts versus second looks: An age-related deficit in selectively refreshing just-active information. Psychological Science, 13, 64-67.
• Mather, M., & Carstensen, L. L. (2005). Aging and motivated cognition: The positivity effect in attention and memory. Trends in Cognitive Sciences, 9, 496-502.
• Mitchell, K.J., Johnson, M.K., Raye, C.L., Mather, M., & D'Esposito, M. (2000). Aging and reflective processes of working memory: Binding and test load deficits. Psychology and Aging, 15, 527-541.
• Nilsson, L-G. (2003). Memory function in normal aging.
• Verhaeghen, P. (2003). Aging and vocabulary scores: A meta-analysis. Psychology and Aging, 18, 332-339.

• Brain puzzles from Infoaging.org
• Researchers Gain New Insights into the Aging Brain
• Memory-related resources from the National Institutes of Health
• What is normal memory loss with aging
• Resources to keep your memory sharp from the AARP
• Recent findings about aging and emotional memory
• Laboratory for Alzheimer's and Parkinson's Disease Research - Prof. Dr. Christian Haass