Methylergonovine

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Methylergonovine
Systematic (IUPAC) name
9,10-didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamide
Identifiers
CAS number 113-42-8
ATC code  ?
PubChem 8226
Chemical data
Formula C20H25N3O2 
Mol. mass 339.432 g/mol
SMILES search in eMolecules, PubChem
Synonyms Methylergonovine
Physical data
Melt. point 172 °C (342 °F)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status

Prescription Only Medicine
Routes  ?


Methylergonovine, also known as methylergometrine, methylergobasin, and d-lysergic acid 1-butanolamide, is a synthetic analogue of ergonovine, a psychedelic alkaloid found in ergot, and many species of morning glory. It is a member of the ergoline family and chemically similar to LSD, ergine, ergonovine, and lysergic acid. Due to its oxytocic properties, it has a medical use in obstetrics. According to Jonathan Ott, methylergonovine has LSD-like actions above 2 milligrams. Clinical dosages are ten times lower.

Methergine (methylergonovine maleate) is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth. It is available as tablets or injection (IM or IV) or in liquid form to be taken orally.

  • cholinergic effects such as nausea, vomiting, and diarrhea
  • cramping
  • dizziness.


v • d • e
Psychedelic lysergamides

AL-LAD • ALD-52 • BU-LAD • CYP-LAD • Diallyllysergamide • DAM-57 • Ergonovine • ETH-LAD • LAE-32 • LSD • LPD-824 • LSM-775 • D-Lysergic acid N-(α-hydroxyethyl)amide • Methylergonovine • MLD-41 • PARGY-LAD • PRO-LAD
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