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This article is about the television series; for the New Zealand hip hop group of the same name, see Misfits of Science (group).

Mark Thomas Miller and Courteney Cox in Misfits of Science

Misfits of Science was a short-lived American superhero fantasy television series that aired on NBC Fridays at 8 PM EST from October, 1985 to October, 1986. It featured a cast of super-powered humans and their madcap adventures. A double-length pilot and 15 additional episodes were created; all episodes but one were broadcast.

• Dean Paul Martin played Dr. Billy Hayes, the non-powered yet undisputed leader of this misfit team. Billy was a research scientist at the Humanidyne Institute.
• Kevin Peter Hall played Dr. Elvin "El" Lincoln, Billy's colleague and close friend. El was a towering black man who gave himself the ability to shrink to doll size via hormonal treatments. The character struggled socially because, despite being very tall and black, he played basketball poorly.
• Mark Thomas Miller was Johnny Bukowski, a.k.a. Johnny B. He was a rock and roll musician who was electrocuted on stage, thus giving him formidable electrical powers. These same powers also granted him some limited superspeed abilities, but they also made him vulnerable to water.
• Courteney Cox played Gloria Dinallo, a troubled telekinetic teen with a history of juvenile delinquency.
• Jennifer Holmes played Gloria's probation officer, Jane Miller. Her character appeared in only the earlier episodes.
• Max Wright portrayed the director of the Humanidyne Institute. Unlike the other cast members, he was not actually considered to be one of the Misfits.
• Mickey Jones played Arthur Beifneiter a.k.a. Ice Man, The team would drive around in an ice cream truck because Ice Man would die if he got too warm, so they kept him in the freezer. Ice Man only appeared in the pilot episode.

1. "Pilot" (October 4, 1985)
2. "Your Place or Mayan?" (October 18, 1985)
3. "Guess What's Coming to Dinner?" (October 25, 1985)
4. "Lost Link" (November 1, 1985)
5. "Sort of Looking for Gina" (November 8, 1985)
6. "Sonar... Yet so Far" (November 15, 1985)
7. "Steer Crazy" (November 29, 1985)
8. "Fumble on the One" (December 6, 1985)
9. "Twin Engines" (December 13, 1985)
10. "Grand Theft Bunny" (December 27, 1985)
11. "Grand Illusion" (January 10, 1986)
12. "Once Upon a Night" (January 17, 1986)
13. "Center of Attention" (January 31, 1986)
14. "Against all Oz" (February 7, 1986)
15. "The Avenging Angel" (February 21, 1986)
16. "Three Days of the Blender" (Unaired)

• Misfits of Science Wiki
• Misfits of Science at the Internet Movie Database
• Courteney Cox in Misfits of Science