Neurophysin I
From Wikipedia, the free encyclopedia
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oxytocin, prepro- (neurophysin I)
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| Identifiers | |
| Symbol | OXT OT |
| HUGO | 8528 |
| Entrez | 5020 |
| OMIM | 167050 |
| RefSeq | NM_000915 |
| UniProt | P01178 |
| Other data | |
| Locus | Chr. 20 p13 |
Neurophysin I is a carrier protein with a size of 10 KDa and containing 90 to 97 aminoacids that transports neurohypophysial hormones along axons, from the hypothalamus to the posterior lobe of the pituitary. This protein is necessary to prevent diffusion of peptide hormones out of the axons. Hormones of the posterior lobe of the pituitary are synthesized in hypothalamic nuclei and are packaged in secretory granules with their respective neurophysins.
Acyl carrier protein - Adaptor protein - F-box protein - GTP-binding protein - Light-harvesting complex - Membrane transport protein
Calcium-binding protein - Calmodulin-binding proteins - Ceruloplasmin - Cholesterylester transfer protein - Iron-binding proteins - Retinol binding protein - Transferrin receptor - Transcobalamins
Follistatin - Growth hormone binding protein - Insulin-like growth factor binding protein - Neurophysins (Neurophysin I, II)
Sex hormone binding globulin/Androgen binding protein - Transcortin - Thyroxine-binding globulin - Transthyretin