Paramethadione

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Paramethadione
Systematic (IUPAC) name
5-ethyl-3,5-dimethyl-oxazolidine-2,4-dione
Identifiers
CAS number 115-67-3
ATC code N03AC01
PubChem 8280
DrugBank APRD00236
Chemical data
Formula C7H11NO3 
Mol. mass 157.167 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding Not significant
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

D(US)
Legal status
Routes  ?

Paramethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.[1]

  • DDB 33106
  • Hoffman D, Chun A (1975). "Paramethadione and metabolite serum levels in humans after a single oral paramethadione dose.". J Pharm Sci 64 (10): 1702-3. PMID 1185541. 
This medical article is a stub. You can help Wikipedia by expanding it.
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Anticonvulsants (N03)

Barbiturates: Barbexaclone, Metharbital, Methylphenobarbital, Phenobarbital, Primidone

Hydantoins: Ethotoin, Fosphenytoin, Mephenytoin, Phenytoin

Oxazolidinediones: Ethadione, Paramethadione, Trimethadione

Succinimides: Ethosuximide, Mesuximide, Phensuximide

Benzodiazepines: Clobazam, Clonazepam, Clorazepate, Diazepam, Lorazepam, Midazolam, Nitrazepam, Temazepam

Carboxamides: Carbamazepine, Oxcarbazepine, Rufinamide Fatty acid derivatives: Valpromide, Valnoctamide

Carboxylic acids: Valproic acid (Sodium valproate & Valproate semisodium), Tiagabine -- GABA analogs: Gabapentin, Pregabalin, Progabide, Vigabatrin

Others:- Monosaccharides: Topiramate -- Aromatic allylic alcohols: Stiripentol -- Ureas: Phenacemide, Pheneturide -- Phenyltriazines: Lamotrigine

Carbamates: Emylcamate, Felbamate, Meprobamate -- Pyrrolidines: Brivaracetam, Levetiracetam, Nefiracetam, Seletracetam

Sulfa drugs: Acetazolamide, Ethoxzolamide, Sultiame, Zonisamide -- Propionates: Beclamide -- Aldehydes: Paraldehyde -- Bromides: Potassium bromide, Sodium bromide

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