Plasminogen activator inhibitor-2

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serpin peptidase inhibitor, clade B (ovalbumin), member 2
Identifiers
Symbol	SERPINB2 PLANH2, PAI2
HUGO	8584
Entrez	5055
OMIM	173390
RefSeq	NM_002575
UniProt	P05120
Other data
Locus	Chr. 18 q21.3

Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor which inactivates tPA & urokinase. It is only present in relevant quantities during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy.

Plasminogen activator inhibitor-1

MeSH Plasminogen+Activator+Inhibitor+2

This biochemistry article is a stub. You can help Wikipedia by expanding it.

v • d • e

Proteins: coagulation

Coagulation factors: - Fibrin (I) - (Pro)thrombin (II) - FV - FVII - FVIII - FIX - FX - FXI - FXII - FXIII - HMWK - vWF - Tissue factor

Inhibitors: Antithrombin - Protein C - Protein S - Protein Z - ZPI - TFPI

Fibrinolysis: Plasmin - tPA/urokinase - PAI-1/2 - α2-AP - TAFI

v • d • e

Serpins

Alpha 1-antichymotrypsin - Alpha 1-antitrypsin - Alpha 2-antiplasmin - Antithrombin - C1-inhibitor - Heat shock protein 47 - Heparin cofactor II - Protein C inhibitor - Plasminogen activator inhibitor-1 - Plasminogen activator inhibitor-2 - Protein Z-related protease inhibitor

noninhibitory: Maspin - Ovalbumin - Thyroxine-binding globulin - Transcortin

Retrieved from "http://en.wikipedia.org../../../p/l/a/Plasminogen_activator_inhibitor-2.html"

Categories: Protein pages needing a picture | Genes on chromosome 18 | Biochemistry stubs | Fibrinolytic system | Serine protease inhibitors

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