Sources
Help build the largest human-edited directory on the web.
Submit a site - Become an editor
Wikipedia. Licensed under the GNU Free Documentation License.
Are you an expert in this subject? Join the discussion and share your knowledge at Wikipedia.org.
Dual Polarisation Interferometry
From Wikipedia, the free encyclopedia
Dual Polarisation Interferometry (DPI)
DPI is an analytical technique used to understand the real-time structure and behaviour of a wide range of molecular systems and interactions through quantitative measurement. DPI has been successful across a range of applications, including proteins, lipids, nucleic acids, lectins, surfactants, polymers, interfacial studies, surface characterisation and nanotechnology.
DPI provides real-time, high-resolution measurements of molecular size, density and mass. Its measurements can be compared directly with complimentary techniques such as NMR, x-ray crystallography and neutron reflection, whilst also being capable of kinetic measurement at far higher sensitivity than first-generation biosensor technologies such as SPR or QCM, which offer only limited and ambiguous information.
DPI utilises a sensing waveguide to measure quantitatively Refractive Index and Thickness in real time of chemistry taking place on a chip surface in a flow through system. As it is an analytical technique the quantitative measurements can be used to infer structural information about the molecular interactions taking place.
See the link for more information about DPI
www.farfield-scientific.com