Povidone-iodine

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Povidone-iodine
Systematic (IUPAC) name
2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine.
Identifiers
CAS number 25655-41-8
ATC code S01AX18 D08AG02 D09AA09 D11AC06 G01AX11 R02AA15
PubChem  ?
Chemical data
Formula (C6H9NO)n·xI
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes topical, when formulated

Povidone-iodine (PVPI) is a water-soluble complex of iodine with polyvinylpyrrolidone (PVP), with from 9.0% to 12.0% available iodine, calculated on a dry basis[1].

PVPI can be further formulated into topical antiseptic products as a solution (with surfactants and/or alcohol), aerosol or ointment at concentrations from 7.5% to 10%. These products are sold over-the-counter (OTC) and used in hospitals for cleansing and disinfecting the skin, preparing the skin preoperatively and treating infections susceptible to iodine.

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