Proteinase 3

From Wikipedia, the free encyclopedia

proteinase 3
Identifiers
Symbol	PRTN3
HUGO	9495
Entrez	5657
OMIM	177020
RefSeq	NM_002777
UniProt	P24158
Other data
Locus	Chr. 19 p13.3

Proteinase 3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.

MeSH Proteinase+3

v • d • e

Endopeptidases: serine proteases/serine endopeptidases

Trypsin - Chymotrypsin - Elastase (Neutrophil, Pancreatic) - Enteropeptidase

Acrosin - Pronase - Proprotein convertases (1, 2) - Subtilisin/Furin

Immune (Chymase, Granzyme, Tryptase, Proteinase 3/Myeloblastin) - Venombin (Ancrod, Batroxobin)

Complement system: Factor B - Factor D - Factor I - MASP (MASP1, MASP2)

Coagulation factors: Thrombin - Factor VIIa - Factor IXa - Factor Xa - Factor XIa - Factor XIIa - Kallikrein (PSA) - Fibrinolysis: Plasmin - Tissue plasminogen activator - Urinary plasminogen activator

Retrieved from "http://en.wikipedia.org../../../p/r/o/Proteinase_3.html"

Categories: Protein pages needing a picture | Genes on chromosome 19 | EC 3.4.21

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