Sources
Help build the largest human-edited directory on the web.
Submit a site - Become an editor
Wikipedia. Licensed under the GNU Free Documentation License.
Are you an expert in this subject? Join the discussion and share your knowledge at Wikipedia.org.
Stephen Christmas
From Wikipedia, the free encyclopedia
Stephen Christmas (12 February 1947- 20 December 1993) was a 5 year old boy when he became the first patient described to have Christmas disease (or Haemophilia B) in 1952 by a group of British doctors.
Steven was born to a British family in Toronto, Canada, and was investigated for his severe bleeding disorder in Oxford, where it was discovered that he was not deficient in Factor VIII, which is normally decreased in classic haemophilia, but a different protein, which received the name Christmas factor in his honour (and later Factor IX).
Stephen was dependent on blood and plasma transfusions, and was infected with HIV in the period during which blood was not routinely screened for this virus. He campaigned for transfusion safety ever since getting infected, but developed AIDS, of which he died in 1993.
- Giangrande PL. Six characters in search of an author: the history of the nomenclature of coagulation factors. Br J Haematol 2003;121:703-12. PMID 12780784.
- Biggs RA, Douglas AS, MacFarlane RG, Dacie JV, Pittney WR, Merskey C, O'Brien JR. Christmas disease: a condition previously mistaken for haemophilia. Br Med J 1952;2:1378-1382. PMID 12997790.