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Systematic bias is a bias resulting from the system, leading on average to systematic errors, in contrast to random errors, which on average cancel each other out.

It is often used in exactly the same manner as the term systemic bias, though systematic is the older and more common form.

An example of systematic bias would be a thermometer that always reads three degrees colder than the actual temperature because of an incorrect initial calibration or labelling, whereas one that gave random values within five degrees either side of the actual temperature would be considered a random error.

Once detected and quantified, it may be easy to compensate for a systematic bias. In the example just given, one knows that the thermometer always reads three degrees below the correct value. Thus, one can simply make a systematic correction by adding three degrees to all readings. In other cases, while a systematic bias is suspected or even detected, no simple correction may be possible because it is impossible to quantify the error. Random errors can in some cases be reduced by repeating the experiment several times and considering an average result; in other cases repetition is not possible.

The existence and causes of systematic bias may be difficult to detect without an independent source of information; the phenomenon of scattered readings resulting from random error calls more attention to itself from repeated estimates of the same quantity than the mutually consistent incorrect results of a biased system.

However, systematic bias can additionally sometimes be used to imply planned human agency. Systematic bias therefore can also mean that the system produces bias as a consequence of consistent, deliberate and planned human interference.

• Bias
• Systemic bias
• Experimenter's bias