TSC1

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Thiazide-sensitive Na/Cl cotransporter (TSC1) is a symporter located on the lumen side of the distal convoluted tubule (DCT) in the kidney. It is encoded by the SLC12A3 gene. (GeneID: 6559)

It is targeted by the benzothiadiazine-type diuretic drugs collectively known as the thiazides.

Defects in this gene can result in Gordon's syndrome.

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