Tetrahydrocannabivarin

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Tetrahydrocannabivarin (THCV, THV)
Chemical name (6aS,10aS)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-
tetrahydro-6H-benzo[c]chromen-1-ol
Chemical formula C19H26O2
Molecular mass 286.41 g/mol
CAS numbers 28172-17-0, 31262-37-0
SMILES CCCC(C=C1O)=CC2=C1[C@]3([H])
[C@](C(C)(C)O2)([H])CCC(C)=C3
Chemical structure of tetrahydrocannabivarin

Tetrahydrocannabivarin, also known as tetrahydrocannabivarol, THCV, or THV, is a psychoactive cannabinoid found in in the hemp plant Cannabis sativa. It is an analog of tetrahydrocannabinol (THC) with the sidechain shortened by two CH2 groups. THCV can be used as a marker compound to differentiate between the consumption of hemp products and synthetic THC (Dronabinol, Marinol).

THCV is found in largest quantities from Indica strains. It has been shown to block CB1 receptors.

Some varieties that produce propyl cannabinoids in significant amounts, over five percent of total cannabinoids, have been found in plants from South Africa, Nigeria, Afghanistan, India, Pakistan and Nepal with THCV as high as 53.69% of total cannabinoids.[1] They usually have moderate to high levels of both THC and CBD and hence have a complex cannabinoid chemistry representing some of the worlds most exotic [cannabis] varieties.[2]


  1. ^ Turner, C.E., Hadley, K.W., and Fetterman, P. 1973. Constituents of Cannabis Sativa L., VI: Propyl Homologues in Samples of Known Geographical Origin. J. Pharm. Sci. 62(10):1739-1741
  2. ^ Deluxe Marijuana Grower's Guide, by Mel Frank [revised edition 1997] pg.37


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