Tiletamine

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Tiletamine chemical structure
Tiletamine
2-ethylamino-2-(2-thienyl) cyclohexanone
IUPAC name
CAS number
 ATC code
PubChem
 DrugBank
Chemical formula C12H17NOS
Molecular weight 223.34
Bioavailability  ?
Metabolism Liver
Elimination half-life  ?
Excretion kidneys
Pregnancy category  ?
Legal status Schedule III (US, in comb. with zolazepam)
Routes of administration intravenous, intramuscular (approved in the US for dogs and cats), subcutaneous

Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically and pharmacologically to other anesthetics in this family such as ketamine and phencyclidine...The appearance when in its raw form is a salt like crystal with a odourless smell .

It is used in veterinary medicine in the compound product Telazol® (tiletamine/zolazepam, 50mg/ml of each in 5ml vial) as an injectable anesthetic. It is sometimes used in combination with xylazine (Rompun®) to tranquilize large mammals such as bears and horses. Telazol is the only commercially available tiletamine product in the USA.

CONTRAINDICATED in patients of an ASA statues of III or greater and in animals with CNS signs, hyperthyroidism, cardiac disease, pancreatic or renal disease, pregnancy, glaucoma, or penetrating eye injuries.

Tiletamine/zolazepam products are classified as Schedule III controlled substances in the United States.

Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
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Retrieved from "http://en.wikipedia.org/wiki/Tiletamine"
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