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- Triamcinolone (1)
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Triamcinolone
From Wikipedia, the free encyclopedia
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Triamcinolone
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| Systematic (IUPAC) name | |
| 9-fluoro-11,16,17-trihydroxy-17- (2-hydroxyacetyl) -10,13-dimethyl-6,7,8,9,10,11,12, 13,14,15,16,17- dodecahydrocyclopenta[a]phenanthren-3-one | |
| Identifiers | |
| CAS number | |
| ATC code | A01 D07AB09, D07XB02, H02AB08, R01AD11, R03BA06, S01BA05 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C21H27FO6 |
| Mol. mass | 394.434 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 68% |
| Metabolism | Hepatic |
| Half life | 88 minutes |
| Excretion | Fecal and renal |
| Therapeutic considerations | |
| Pregnancy cat. |
A (Au), C (US) |
| Legal status | |
| Routes | Oral, topical, IM, intra-articular, intrasynovial |
Triamcinolone (trade names Kenalog, Aristocort, Nasacort, Tri-Nasal, Triderm, Azmacort, Trilone, Volon A, Tristoject, Fougera;) is a synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream.
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They are also used in the post-operative period of certain cosmetic surgery procedures, notably rhinoplasty. Injected into the supra-tip area, they may help to alleviate stubborn swelling and decrease the presence of scar tissue.
Topical triamcinolone acetonide paste is often prescribed for mouth or gum irritation following dental procedures.
Triamcinolone is occasionally used to treat severe cases of hayfever.[1]
Different triamcinolone salts are available, including acetonide, hexacetonide and diacetate.
Triamcinolone acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone.
- ^ Hayfever (allergic rhinitis) - BUPA
- MedlinePlus DrugInfo medmaster-a601124
- Cautions for Triamcinolone Use
- Significant drug interactions with triamcinolone
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| Caries prophylactic agents | Sodium fluoride - Sodium monofluorophosphate - Olaflur - Stannous fluoride |
| Anti-infectives and antiseptics | Hydrogen peroxide - Chlorhexidine - Amphotericin B - Polynoxylin - Domiphen - Oxyquinoline - Neomycin - Miconazole - Natamycin - Hexetidine - Tetracycline - Benzoxonium chloride - Tibezonium iodide - Mepartricin - Metronidazole - Clotrimazole - Sodium perborate - Chlortetracycline - Doxycycline - Minocycline - Eugenol |
| Corticosteroids | Triamcinolone - Dexamethasone - Hydrocortisone |
| Other | Epinephrine/Adrenalone - Benzydamine - Acetylsalicylic acid - Amlexanox |
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| Mineralocorticoids | Aldosterone - Fludrocortisone - Desoxycortone |
| Glucocorticoids | Betamethasone - Dexamethasone - Fluocortolone - Methylprednisolone - Paramethasone - Prednisolone - Prednisone - Triamcinolone - Hydrocortisone - Cortisone - Prednylidene - Rimexolone - Deflazacort - Cloprednol - Meprednisone - Cortivazol |
| Anticorticosteroids | Trilostane |
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| Topical: sympathomimetics, plain | Cyclopentamine - Ephedrine - Phenylephrine - Oxymetazoline - Tetryzoline - Xylometazoline - Naphazoline - Tramazoline - Metizoline - Tuaminoheptane - Fenoxazoline - Tymazoline - Epinephrine |
| Topical: antiallergic agents, excluding corticosteroids | Cromoglicic acid - Levocabastine - Azelastine - Antazoline - Spaglumic acid - Thonzylamine - Nedocromil - Olopatadine |
| Topical: corticosteroids | Beclometasone - Prednisolone - Dexamethasone - Flunisolide - Budesonide - Betamethasone - Tixocortol - Fluticasone - Mometasone furoate - Triamcinolone |
| Topical: other nasal preparations | Calcium hexamine thiocyanate - Retinol - Ipratropium bromide - Ritiometan - Mupirocin - Hexamidine - Framycetin |
| Systemic use: Sympathomimetics | Phenylpropanolamine - Pseudoephedrine - Phenylephrine |
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