URB597

From Wikipedia, the free encyclopedia

urb597
Chemical name (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)
-cyclohexylcarbamate
Chemical formula C20H22N2O3
Molecular mass 338.4 g/mol
CAS number 546141-08-6
Chemical structure of urb597

URB597 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery. In pre-clinical laboratory tests researchers found URB597 increased the production of endocannabinoids resulting in measurable antidepressant effects.

URB597 is also known as KDS-4103. KDS-4103 is being developed by Kadmus Pharmaceuticals, Inc. for clinical trials in humans. Kadmus claims, on their website (linked below) that this class of compounds may have antidepressant, anti-anxiety, and pain-killing effects.


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